Endocrine Abstracts

We describe two similar but distinct cases of newly presenting coexistent adrenocortical insufficiency and type 1 diabetes.Case 1; an 18 yr old woman presented with a two week history of polydipsia, polyuria and accelerated weight loss. Random glucose 20.2 mmol/L but no evidence of ketoacidosis. She was thin, pigmented, hypotensive and dehydrated and confirmed one years weight loss, lethargy, abdominal pain and occasional vomiting. Short synacthen test c...

Introduction: Short synacthen test (SST) is of value in assessing the adequacy of hypothalamic–pituitary–adrenal axis (HPA). Although it is extensively used, it is unclear at what morning cortisol concentration one should consider performing the SST.Methods: Retrospective observational study of consecutively performed SST (250 μg) between January 2009 and March 2010. Plasma cortisol was measured by enzyme immunoassay (Siemens Advia, Siemen...